KU70 Antibody

Datasheet

Code	CSB-PA748662XA01OFG
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Product Details

Full Product Name

Rabbit anti-Oryza sativa subsp. japonica (Rice) KU70 Polyclonal antibody

Uniprot No.

Q7F1M0

Target Names

KU70

Alternative Names

KU70 antibody; Os07g0184900 antibody; LOC_Os07g08729 antibody; OJ1046_F10.128 antibody; OsJ_23357 antibody; OsJ_23359 antibody; ATP-dependent DNA helicase 2 subunit KU70 antibody; OsKU70 antibody; EC 3.6.4.12 antibody; ATP-dependent DNA helicase 2 subunit 1 antibody; ATP-dependent DNA helicase II 70 kDa subunit antibody

Raised in

Rabbit

Species Reactivity

Oryza sativa subsp. japonica (Rice)

Immunogen

Recombinant Oryza sativa subsp. japonica (Rice) KU70 protein

Immunogen Species

Oryza sativa subsp. japonica (Rice)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Required for the maintenance of chromosome stability and normal developmental growth. Plays a role in maintaining telomere length. Acts as a negative regulator in telomere homeostasis.

Gene References into Functions

Ku70 knockdown leads to decreased Agrobacterium-mediated stable transformation and enhanced homologous recombination in rice. PMID: 23050791
These results suggest that OsKu70 is required for the maintenance of chromosome stability and normal developmental growth in rice plants. PMID: 19923234

Subcellular Location

Nucleus.

Protein Families

Ku70 family

Tissue Specificity

Expressed ubiquitously.

Database Links

KEGG: osa:4342584

STRING: 39947.LOC_Os07g08729.1

UniGene: Os.51984

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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KU70 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background