Kmo Antibody

Datasheet
Code CSB-PA012475ZA01RA
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Product Details

Full Product Name Rabbit anti-Rattus norvegicus (Rat) Kmo Polyclonal antibody
Uniprot No. O88867
Target Names Kmo
Alternative Names Kmo antibody; Kynurenine 3-monooxygenase antibody; EC 1.14.13.9 antibody; Kynurenine 3-hydroxylase antibody
Raised in Rabbit
Species Reactivity Rattus norvegicus
Immunogen Recombinant Rat Kynurenine 3-monooxygenase (Kmo), partial (1-384AA)
Immunogen Species Rattus norvegicus (Rat)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

Target Data

Function Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Subcellular Location Mitochondrion outer membrane, Multi-pass membrane protein
Protein Families Aromatic-ring hydroxylase family, KMO subfamily
Tissue Specificity Highest activity in liver and kidney. Low activity in spleen, stomach, intestinal tract, esophagus, heart and lung.
Database Links

KEGG: rno:59113

STRING: 10116.ENSRNOP00000005005

UniGene: Rn.35029

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