larp Antibody

Code CSB-PA894663XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) larp Polyclonal antibody
Uniprot No.
Target Names
larp
Alternative Names
larp antibody; CG42551 antibody; La-related protein 1 antibody; dLarp antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) larp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
RNA-binding protein required during male meiosis and development of the syncytial embryo. Binds poly-(A) tails of mRNAs and regulates their expression by regulating their stability or translation.
Gene References into Functions
  1. Larp4B is a member of La-related proteins (LARPs) containing an LA motif and an adjacent RNA recognition motif (RRM), and play diverse roles in RNA metabolism. Overexpression of La-related protein 4B (larp4B) reduces cell and organ sizes in Drosophila. PMID: 29462618
  2. The larp mutant males exhibited multiple meiotic phenotypes such as defects in chromosome segregation, a failure of cytokinesis, and unequal mitochondrial partition PMID: 17951964
  3. the syncytial mitotic cycles and male meiosis should have a particularly sensitive requirement for Larp proteins in regulating not only transcript stability but also potentially the translation of mRNAs PMID: 19631203
Subcellular Location
Mitochondrion. Cytoplasm, cytosol.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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