Lk Antibody

Code CSB-PA305624XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Lk Polyclonal antibody
Uniprot No.
Target Names
Lk
Alternative Names
Lk antibody; pp antibody; CG13480Leucokinin antibody; DLK antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Lk protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts through intracellular calcium in Malpighian tubule stellate cells to raise chloride conductance.
Gene References into Functions
  1. hunger induces reduction of responses to noxious heat through the Lk/Lkr signaling pathway in Drosophila. PMID: 29559237
  2. Disruption of Kinin signaling leads to defective air-filling during all larval stages. PMID: 29386394
  3. Kinin neuropeptide modulates desiccation and starvation tolerance in Drosophila melanogaster. PMID: 26896569
  4. Data show that mutations in the leucokinin neuropeptide (leuc) and leucokinin receptor (lkr) genes cause phenotypes in which Drosophila adults have an increase in meal size and a compensatory reduction in meal frequency. PMID: 20493701
  5. Apterous is necessary for expression of the Leucokinin neuropeptide in a pair of brain neurons located in the lateral horn region of the protocerebrum PMID: 12541314

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Subcellular Location
Secreted.
Database Links

KEGG: dme:Dmel_CG13480

STRING: 7227.FBpp0075465

UniGene: Dm.3002

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