lem-2 Antibody

Code CSB-PA893176XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans lem-2 Polyclonal antibody
Uniprot No.
Target Names
lem-2
Alternative Names
lem-2; W01G7.5; LEM protein 2; Ce-MAN1; MAN1 homolog
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans lem-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Essential protein involved in chromosome segregation and cell division, probably via its interaction with lmn-1, the main component of nuclear lamina. Has some overlapping function with emr-1. May play a role in radiation-induced DNA damage repair response.
Gene References into Functions
  1. LEM-2 is localized to the nuclear membrane in every cell of C. elegans embryos. The genes in LEM-2 subdomains tend to be inactive, while those in gaps tend to be active. PMID: 21176223
Subcellular Location
Nucleus envelope. Nucleus inner membrane; Multi-pass membrane protein. Chromosome.
Tissue Specificity
Ubiquitous.
Database Links

KEGG: cel:CELE_W01G7.5

STRING: 6239.W01G7.5

UniGene: Cel.14238

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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