Letm1 Antibody

Code CSB-PA309356XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Letm1 Polyclonal antibody
Uniprot No.
Target Names
Letm1
Alternative Names
Letm1 antibody; anon-60Da antibody; CG4589Mitochondrial proton/calcium exchanger protein antibody; Leucine zipper-EF-hand-containing transmembrane protein 1 antibody; dLetm1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Letm1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion.
Gene References into Functions
  1. These results demonstrate the function of DmLETM1 as a mitochondrial osmoregulator. PMID: 20026556
  2. CG4589, the Drosophila homolog of the human gene Letm1, was identified as a gene strongly affecting [Ca2+]mito and [H+]mito responses PMID: 19797662
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
LETM1 family
Database Links

KEGG: dme:Dmel_CG4589

STRING: 7227.FBpp0072255

UniGene: Dm.7406

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