IMDH2 Antibody

Code CSB-PA310130XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) IMDH2 Polyclonal antibody
Uniprot No.
Target Names
IMDH2
Alternative Names
IMDH2 antibody; IMD2 antibody; IMDH antibody; IPMDH2 antibody; At1g80560 antibody; T21F11.11 antibody; 3-isopropylmalate dehydrogenase 2 antibody; chloroplastic antibody; 3-IPM-DH 2 antibody; AtIMDH2 antibody; AtIMDH3 antibody; IMDH 2 antibody; EC 1.1.1.85 antibody; Beta-IPM dehydrogenase 2 antibody; Isopropylmalate dehydrogenase 2 antibody; AtIMD2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana IMDH2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism). Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Required during pollen development and involved in embryo sac development.
Gene References into Functions
  1. the x-ray crystal structures of Arabidopsis thaliana IPMDH2 (AtIPMDH2) in complex with either isopropylmalate and Mg(2+) or NAD(+) These structures reveal conformational changes that occur upon ligand binding and provide insight on the active site of the enzyme. PMID: 27137927
Subcellular Location
Plastid, chloroplast stroma.
Protein Families
Isocitrate and isopropylmalate dehydrogenases family
Tissue Specificity
Expressed at low levels in seedlings, cotyledons, hypocotyls, flowers, roots, pollen, leaves and stems.
Database Links

KEGG: ath:AT1G80560

STRING: 3702.AT1G80560.1

UniGene: At.5371

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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