lin-10 Antibody

Code CSB-PA515709XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans lin-10 Polyclonal antibody
Uniprot No.
Target Names
lin-10
Alternative Names
lin-10 antibody; C09H6.2 antibody; Protein lin-10 antibody; Abnormal cell lineage protein 10 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans lin-10 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required specifically for the determination of 3 vulval precursor cell fates P5.p, P6.p and P7.p during late second and early third larval stages; required for basolateral localization of receptor tyrosine kinase let-23. Could have a general but redundant role in development, functioning in diverse cell lineages to control cell fates. Regulates the trafficking of the glr-1 subunit of AMPA-type glutamate receptors (AMPRs) in the ventral nerve cord. This may be partly through interacting with the small GTPase rab-6.2 in its active GTP-bound state.
Gene References into Functions
  1. LIN-10 uses distinct modular domains for its functions in neurons and epithelial cells PMID: 15647374
Subcellular Location
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasm. Cell junction, synapse. Perikaryon.
Tissue Specificity
Expressed in vulval epithelial cells and neurons.
Database Links

KEGG: cel:CELE_C09H6.2

STRING: 6239.C09H6.2a

UniGene: Cel.4906

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