lft Antibody

Code CSB-PA215856XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) lft Polyclonal antibody
Uniprot No.
Target Names
lft
Alternative Names
lft antibody; CG13139 antibody; Protein limb expression 1 homolog antibody; lowfat antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) lft protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the Fat (ft) signaling pathway that functions in normal development of various organs such as the wing and leg. In developing imaginal disks, involved in regulating both the protein levels and apical localization of ft and ds. Involved in establishing planar cell polarity (PCP) along the anterior-posterior axis of the wing (the early Fz signaling event), probably by acting upstream of ds and ft to regulate Fz activity.
Gene References into Functions
  1. identification of a conserved cytoplasmic protein, Lowfat (Lft, CG13139), as a modulator of Fat signaling. PMID: 19710173
Subcellular Location
Apical cell membrane; Peripheral membrane protein. Cytoplasm.
Protein Families
LIX1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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