LAP2 Antibody

Code CSB-PA604632XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) LAP2 Polyclonal antibody
Uniprot No.
Target Names
LAP2
Alternative Names
LAP2 antibody; YNL045W antibody; N2535 antibody; Leucine aminopeptidase 2 antibody; EC 3.4.11.- antibody; Epoxide hydrolase antibody; EC 3.3.2.10 antibody; Leucyl aminopeptidase yscIV antibody; AP IV antibody; Leukotriene A-4 hydrolase homolog antibody; LTA-4 hydrolase antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) LAP2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
Gene References into Functions
  1. The structures of both native leukotriene A4 hydrolase and the hydrolase in complex with bestatin were solved. These structures show leukotriene A4 is bound in a partially-obstruced protected cavity in the active site of the human hydrolase. PMID: 21146536
  2. the conserved tyrosine residue of Saccharomyces cerevisiae leukotriene A4 hydrolase stabilizes the transition state of the peptidase activity PMID: 16597475
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Peptidase M1 family
Database Links

KEGG: sce:YNL045W

STRING: 4932.YNL045W

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