lon Antibody

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Code	CSB-PA359319XA01FQR
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Target Background

Product Details

Full Product Name

Rabbit anti-Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) lon Polyclonal antibody

Uniprot No.

P0A9M1

Target Names

lon

Alternative Names

lon antibody; c0555 antibody; Lon protease antibody; EC 3.4.21.53 antibody; ATP-dependent protease La antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Immunogen

Recombinant Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) lon protein

Immunogen Species

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.

Subcellular Location

Cytoplasm.

Protein Families

Peptidase S16 family

Database Links

KEGG: ecc:c0555

STRING: 199310.c0555

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