LON2 Antibody

Code CSB-PA524642XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) LON2 Polyclonal antibody
Uniprot No.
Target Names
LON2
Alternative Names
LON2 antibody; At5g47040 antibody; MQD22.18 antibody; Lon protease homolog 2 antibody; peroxisomal antibody; EC 3.4.21.53 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana LON2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
Gene References into Functions
  1. pexophagy is accelerated when the LON2 protease is disabled PMID: 24413187
  2. atg2, atg3, and atg7 mutations suppressed lon2 defects in auxin metabolism and matrix protein processing and rescued the abnormally large size and small number of lon2 peroxisomes PMID: 24179123
  3. LON2- and autophagy-dependent pathways are interdependent, with the chaperone function of LON2 suppressing autophagic peroxisome degradation PMID: 24739336
  4. LON2 is necessary for IBA-stimulated lateral root formation and for sustained matrix protein import into peroxisomes. PMID: 19748917
Subcellular Location
Peroxisome matrix.
Protein Families
Peptidase S16 family
Database Links

KEGG: ath:AT5G47040

STRING: 3702.AT5G47040.1

UniGene: At.8585

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