Lsd-2 Antibody

Code CSB-PA892915XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Lsd-2 Polyclonal antibody
Uniprot No.
Target Names
Lsd-2
Alternative Names
Lsd-2 antibody; CG9057 antibody; Lipid storage droplets surface-binding protein 2 antibody; Lsd2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Lsd-2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Essential for embryogenesis. Required for normal deposition of neutral lipids in the oocyte.
Gene References into Functions
  1. that HDAC6 is associated physically with the chaperone protein dHsc4/Hsc70 to maintain the proteostasis of PLIN2 PMID: 28966044
  2. Perilipin homologus, LSD2 plays a role in sleep regulation and prevents learning impariment following sleep loss. PMID: 20824166
  3. Lsd2, one of only two PAT domain-encoding genes in the Drosophila genome acts in a Perilipin-like manner, suggesting that components regulating homeostasis of lipid-based energy storage at the lipid droplet membrane are evolutionarily conserved. PMID: 12676093
  4. Lsd2 has an evolutionarily conserved function in lipid metabolism PMID: 14550535
  5. Lsd-2 is expressed and controls lipid storage in wing imaginal discs. PMID: 15704138
  6. LSD2 regulates both lipid metabolism and transport along microtubules in embryos. PMID: 16051169

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Subcellular Location
Cytoplasm. Lipid droplet.
Protein Families
Perilipin family
Tissue Specificity
Ubiquitous expression in early embryos. At stage 5 expression is restricted to the pole cells. At stage 11 expression is seen in the amnioserosa, refined to the fat body and midgut by stage 14. Also seen in the hindgut by the end of embryogenesis. Express
Database Links

KEGG: dme:Dmel_CG9057

UniGene: Dm.4079

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