Ns3 Antibody

Code CSB-PA895703XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ns3 Polyclonal antibody
Uniprot No.
Target Names
Ns3
Alternative Names
Ns3 antibody; l(1)G0431 antibody; CG14788 antibody; Large subunit GTPase 1 homolog antibody; EC 3.6.1.- antibody; Nucleostemin-3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ns3 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
GTPase required for the nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm. Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control.
Gene References into Functions
  1. The ribosome biogenesis role of NS3 is essential for proper rates of translation in all tissues and is necessary for functions of growth-promoting neurons. PMID: 23436180
Subcellular Location
Cytoplasm. Note=Punctate distribution.
Protein Families
TRAFAC class YlqF/YawG GTPase family, LSG1 subfamily
Tissue Specificity
Expressed in larval serotonergic neurons.
Database Links

KEGG: dme:Dmel_CG14788

STRING: 7227.FBpp0070284

UniGene: Dm.4650

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