luxS Antibody

Code CSB-PA518511ZA01BRJ
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Product Details

Full Product Name
Rabbit anti-Bacillus subtilis (strain 168) LUXS Polyclonal antibody
Uniprot No.
Target Names
LUXS
Alternative Names
luxS antibody; ytjB antibody; BSU30670 antibody; S-ribosylhomocysteine lyase antibody; EC 4.4.1.21 antibody; AI-2 synthesis protein antibody; Autoinducer-2 production protein LuxS antibody
Raised in
Rabbit
Species Reactivity
Bacillus subtilis
Immunogen
Recombinant Bacillus subtilis luxS protein
Immunogen Species
Bacillus subtilis (strain 168)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Gene References into Functions
  1. Structural study of catalytically inactive mutant (Cys84Ala) of cobalt (Co2+)-substituted Bacillus subtilis LuxS in complex with the 2-ketone intermediate provides strong support for the proposed Lewis acid function of the metal ion during catalysis. PMID: 15751951
  2. B. subtilis luxS is a growth-phase-regulated gene that produces active AI-2 able to mediate the interspecific activation of light. PMID: 16740951
Protein Families
LuxS family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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