M Antibody

Code CSB-PA806800ZA01VBF
Uniprot No. Q8B0I2
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Vesicular stomatitis Indiana virus Matrix protein (M) (1-229AA)
Raised in Rabbit
Species Reactivity Vesicular stomatitis Indiana virus
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Matrix protein, M
Immunogen Species Vesicular stomatitis Indiana virus (strain 98COE North America) (VSIV)
Gene Names M
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shutoff presumably inhibits interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell (By similarity).
Subcellular Location Virion membrane, Peripheral membrane protein, Host endomembrane system, Peripheral membrane protein, Host nucleus membrane, Peripheral membrane protein
Protein Families Vesiculoviruses matrix protein family

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