slpr Antibody

Datasheet

Code	CSB-PA850200XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) slpr Polyclonal antibody

Uniprot No.

Q95UN8

Target Names

slpr

Alternative Names

slpr antibody; Mlk2 antibody; CG2272 antibody; Mitogen-activated protein kinase kinase kinase antibody; EC 2.7.11.25 antibody; Mixed lineage kinase antibody; Protein slipper antibody; dMLK antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) slpr protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Activates the JUN N-terminal pathway during dorsal closure.

Gene References into Functions

Slpr is dispensable for Eiger/TNF-induced cell death and innate immune response mediated by Tak1 PMID: 24429281
a posttranslational modification on Slpr, at a conserved site among MAP3K mixed lineage kinase family members, which bolsters stress resistance with negligible effects on JNK-dependent developmental proces PMID: 22848763
The N-terminal half of Slpr is involved in regulating JNK signaling. PMID: 20736302
activated by ceramide PMID: 12504027
evidence that dMLK/slipper can be classified as a MAPKKK family member in the activation of the JNK pathway PMID: 12676357
SLPR overexpression can induce ectopic Jun-N-terminal kinase kinase signaling; SLPR protein is enriched at the epithelial cell cortex. PMID: 16888342

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Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily

Tissue Specificity

Expressed both maternally and zygotically. Expressed uniformly in large quantities in the early embryo (stages 1-4). In the late embryo, expression is ubiquitous, but expression levels are dramatically reduced. Expressed in the adult head and thorax, and

Database Links

KEGG: dme:Dmel_CG2272

STRING: 7227.FBpp0292850

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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slpr Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background