MAF1 Antibody

1. correlation between CCA synthesis and Pol III regulation by Maf1 could be important in coordination of tRNA transcription, processing and regulation of translation PMID: 27575455
2. Sub1 and Maf1 also exhibit an opposite role on yeast chronological life span PMID: 25531541
3. PKA modulates Maf1 protein abundance for stress and lifespan but not growth PMID: 25720796
4. Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway. PMID: 22919049
5. Recovery of RNA polymerase III transcription from the glycerol-repressed state: revisiting the role of protein kinase CK2 in Maf1 phosphoregulation. PMID: 22810236
6. Maf1-mediated transcription control and nuclear export by Los1 are two major stages of tRNA biosynthesis that are regulated by environmental conditions in a coordinated manner. PMID: 21940626
7. an important role of CK2-mediated Maf1 phosphorylation in triggering Pol III activation. PMID: 21383183
8. Study reports the crystal structure of Maf1 and cryo-electron microscopic structures of Pol III, an active Pol III-DNA-RNA complex, and a repressive Pol III-Maf1 complex. PMID: 20887893
9. The authors show that TORC1 interacts with Maf1 in vivo and phosphorylates Maf1 in vitro, and regulates Maf1 nucleoplasm-to-nucleolus translocation. PMID: 19574957
10. Maf1 does not differentially sequester Brf1 or pol III under repressing conditions. The results suggest that Maf1 functions by a non-stoichiometric mechanism to repress pol III transcription PMID: 15590667
11. Under repressing conditions, Maf1 is dephosphorylated and accumulates in the nucleus, and Pol III-Maf1 interaction increases. PMID: 16762835
12. Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression PMID: 16762836
13. Nuclear accumulation of Maf1 is required for transcriptional repression and is regulated by two nuclear localization sequences in the protein. PMID: 17005718
14. Transcription regulation by Maf1 is not limited to stress but is important for the switch between fermentation and respiration. PMID: 17785443
15. phosphorylation of Maf1 inside the nucleus acts both directly by decreasing of Maf1-mediated repression of Pol III and indirectly by stimulation of Msn5 binding and export of nuclear Maf1 to the cytoplasm PMID: 18445601
16. Maf1 functions in parallel pathways to negatively regulate ribosomal protein mRNA and tRNA synthesis. PMID: 18604275

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KEGG: sce:YDR005C

STRING: 4932.YDR005C