Magi1 Antibody

1. the interaction between nephrin and MAGI-1 regulates Rap1 activation in podocytes to maintain long term slit diaphragm structure PMID: 27707879
2. Cx32 expression is in part related to induction of tight junctions through modulation of Magi1 expression in an immortalized hepatic cell line. PMID: 15558322
3. ARIP1 and ARIP2 are co-expressed in some nerve cells and their biological activities are distinct. PMID: 23523645
4. Data conclude that the up-regulation of sdk-1 in podocytes is an important pathogenic factor in glomerulosclerosis and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 function. PMID: 20562105
5. Depletion of MAGI-1 from photorecptors by RNA interference blocks synaptic localization of Sidekick-2 in photoreceptors without affecting localization of postsynaptic density (PSD)-95. PMID: 20219992
6. MAGI-1 together with JAM4 provides an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells PMID: 12773569
7. We found MAGI-1 to be associated with cell-cell contacts in human umbilical vein endothelial cells (HUVECs) and in mouse endothelium, where it colocalizes with ESAM. PMID: 15383320
8. MAGI-1 cleavage appears to be an important step in the disassembly of cell-cell contacts during apoptosis. PMID: 17191119

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KEGG: mmu:14924

STRING: 10090.ENSMUSP00000086730

UniGene: Mm.217216