malG Antibody

Code CSB-PA304701XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) malG Polyclonal antibody
Uniprot No.
Target Names
malG
Alternative Names
malG; b4032; JW3992; Maltose/maltodextrin transport system permease protein MalG
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) malG protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
Gene References into Functions
  1. Data indicate that MalFGK2 transporter is comprised of two membrane proteins, MalF and MalG, and the nucleotide-binding domain, which controls the conformation of MalFG, is composed of the homodimeric MalK subunit. PMID: 27059961
  2. Data suggest that the binding and conformational change of maltose transporter (MalFGK2) may provide some insights into the understanding of the mechanism of ABC transporters. PMID: 24865820
  3. using x-ray crystallography, study captured the maltose transporter in an intermediate step between the inward- and outward-facing states PMID: 21566157
  4. analysis of the MalFGK2 mechanism for coupling ATP hydrolysis to substrate translocation without direct recognition of substrate PMID: 20147285
  5. ATP-driven MalK dimer closure and reopening are crucial steps in the translocation cycle of the intact maltose transporter MalFGK2 PMID: 17545154
  6. substrate availability is communicated from MalE to the MalK dimer via extracytoplasmic loops of MalFG PMID: 17961142
  7. 2.8-A crystal structure of the intact maltose transporter in complex with the maltose-binding protein, maltose and ATP PMID: 18033289

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Subcellular Location
Cell inner membrane; Multi-pass membrane protein.
Protein Families
Binding-protein-dependent transport system permease family, MalFG subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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