mbl Antibody

Code CSB-PA519412XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) mbl Polyclonal antibody
Uniprot No.
Target Names
mbl
Alternative Names
mbl antibody; mm antibody; CG33197Protein muscleblind antibody; Protein mindmelt antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) mbl protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for terminal differentiation of photoreceptor cells. Vital for embryonic development.
Gene References into Functions
  1. These results demonstrate the relevance of Mbl sequestration caused by expanded-CUG-repeat RNA in cardiac dysfunctions in Myotonic dystrophy type 1. PMID: 29592894
  2. Data show that two miRNAs, dme-miR-277 and dme-miR-304, that differentially regulate muscleblind RNA isoforms PMID: 27805016
  3. Drosophila muscleblind codes for proteins with one and two tandem zinc finger motifs PMID: 22479576
  4. This study suggested that the mbl gene function is required for the normal development of neural substrates that regulate female sexual receptivity. PMID: 19169922
  5. Mbl recognizes complex RNA secondary structures. PMID: 18557632

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Subcellular Location
Nucleus.
Protein Families
Muscleblind family
Tissue Specificity
Expressed in embryonic muscle cells.
Database Links

KEGG: dme:Dmel_CG33197

STRING: 7227.FBpp0297556

UniGene: Dm.2992

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