MCA2 Antibody

Datasheet

Code	CSB-PA662986XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MCA2 Polyclonal antibody

Uniprot No.

Q3EBY6

Target Names

MCA2

Alternative Names

MCA2; At2g17780; T17A5.4; Protein MID1-COMPLEMENTING ACTIVITY 2

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana MCA2 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Calcium-permeable stretch-activated channel component. Probably involved in mechanosensing and in mechano-stimulated calcium uptake mechanism.

Gene References into Functions

MCA2 is involved in the cold-induced elevation of [Ca2+]cyt, cold tolerance, and CBF/DREB1-independent cold signaling. PMID: 29323146
Transmembrane Topologies of Ca2+-permeable Mechanosensitive Channels MCA1 and MCA2 in Arabidopsis thaliana. PMID: 26555262
MCA2 from Arabidopsis thaliana is involved in mechanical stress-induced Ca2+ influx. PMID: 24475319
The N-terminal half of both proteins with the EF hand-like region is necessary and sufficient for Ca(2+) uptake and that the coiled-coil motif regulates MCA1 negatively and MCA2 positively. PMID: 21949028
MCA2 has a distinct role in Ca2+ uptake in roots and an overlapping role with MCA1 in plant growth. PMID: 20097794

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Subcellular Location

Cell membrane; Single-pass membrane protein.

Tissue Specificity

Expressed in roots, leaves, stems, flowers and siliques. In the root, high levels of expression in vascular tissues, in the stele and endodermis, but no expression in the cortex, epidermis, root cap, promeristem and adjacent elongation zone of the primary

Database Links

KEGG: ath:AT2G17780

STRING: 3702.AT2G17780.1

UniGene: At.40099

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Service

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Protein Service

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Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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MCA2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background