mdfA Antibody

1. MdfA has exceptional promiscuous capabilities not only in its interaction with a plethora of chemically dissimilar compounds, but also concerning the various faces of its modes of energy consumption. [review] PMID: 28951231
2. Crystallization and X-ray diffraction analysis of the multidrug-resistance transporter MdfA from Escherichia coli has been reported. PMID: 28695852
3. The MdfA structure consists of four pseudo-symmetrical, three-helix repeats, consistent with the typical structure of an MFS transporter. PMID: 26238402
4. The mdfA gene can function as transporter responsible for multidrug resistance, and also mediated the synergistic function with its surrounding genes in conjugative plasmids. PMID: 24684286
5. GlpG is able to recognize and cleave truncated forms of MdfA but not the intact protein. PMID: 19919105
6. results show that MdfA confers extreme alkaline pH resistance and allows the growth of transformed cells under conditions that are close to those used normally by alkaliphiles (up to pH 10) by maintaining a physiological internal pH PMID: 15371593
7. results suggest that in the absence of specific chloramphenicol selection pressure, the cmlA gene is maintained by virtue of gene linkage to genes encoding resistance to antimicrobials that are currently approved for use in food animals PMID: 15668031
8. Arg112 is important for multidrug transport by MdfA. PMID: 16274234
9. properties of MdfA including its multidrug recognition capacity, proton recognition determinants, aspects of energy utilization, and physiological role [review] PMID: 17114895
10. the Mdr-binding pocket of MdfA is conformationally sensitive PMID: 19808670
11. In this study, we got an evidence that MdfA is a chloramphenicol/H+ antiporter. PMID: 9644262

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KEGG: ag:CAA69997

STRING: 316385.ECDH10B_0911