MDM34 Antibody

Code CSB-PA346425XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MDM34 Polyclonal antibody
Uniprot No.
Target Names
MDM34
Alternative Names
MDM34 antibody; MMM2 antibody; YGL219C antibody; Mitochondrial distribution and morphology protein 34 antibody; Mitochondrial outer membrane protein MMM2 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MDM34 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
Gene References into Functions
  1. Mdm34 and Mdm12, 2 components of the endoplasmic reticulum-mitochondrial encounter structure, are ubiquitinated by the E3 ligase Rsp5 PMID: 27846375
  2. Pex11 and Mdm34 physically interact. PMID: 25769804
  3. These results indicate that Mdm34p is a physiologically important target of Mdm30p. PMID: 18775025
Subcellular Location
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein Families
MDM34 family
Database Links

KEGG: sce:YGL219C

STRING: 4932.YGL219C

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