MIA40 Antibody

1. the question whether parasite Erv homologs might also exert the function of Mia40 was addressed in another set of complementation assays. However, neither the KISS domain nor other truncated or mutant LtErv constructs were able to rescue yeast cells that lack ScMia40 PMID: 29310075
2. Plant Erv1, unlike its homologs in fungi and animals, can promote protein import and oxidative protein folding in the IMS independently of the oxidoreductase Mia40. PMID: 29117860
3. The authors show that the substrate-binding domain of Mia40 is both necessary and sufficient to promote protein import, indicating that trapping by Mia40 drives protein translocation. PMID: 27343349
4. Mia40 catalyses the oxidative folding of disulphide-containing proteins in the mitochondria. PMID: 24407114
5. Mia40 role in mitochondrial oxidative protein folding and import PMID: 24983157
6. Data indicate that in addition to its thiol oxidase function, Mia40 is active as a disulfide reductase and isomerase. PMID: 25451030
7. Mia40 oxidizes Mrp10 during import into mitochondria. PMID: 24360785
8. Saccharomyces cerevisiae Mia40 is a mitochondrial iron-sulfur protein. PMID: 23834247
9. Atp23 was identified as a novel substrate of Mia40. Oxidation of Atp23 is not essential for its import; an Atp23 variant in which all ten cysteine residues were replaced by serine residues still accumulates in mitochondria in a Mia40-dependent manner. PMID: 22990235
10. Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state. PMID: 22705944
11. The oxidoreductase of the mitochondrial disulfide relay, Mia40, controls oxidative folding of domain I of the copper chaperone Ccs1 whereby controlling the cellular distribution of Ccs1 and, consequently, active Superoxide dismutase 1 (Sod1). PMID: 21865594
12. The 9-aa internal peptide making up the mitochondrial intermembrane space -targeting signal (ITS) involved in docking with Mia40 is characterized. PMID: 20026652
13. Mia40 is the first essential component of a specific translocation pathway of metal-binding intermembrane space proteins. PMID: 15620710
14. Mia40 acts as a trans receptor in the biogenesis of the Tim9-Tim10 chaperone complex of mitochondria PMID: 17553782
15. Results show that oxidative folding of Tims 9 and 10 is mediated by site-specific docking onto Mia40 in the mitochondrial intermembrane space. PMID: 17680986
16. analysis of how mitochondrial biogenesis switches the sorting pathway of the intermembrane space receptor Mia40 PMID: 18779329
17. Study shows that Hot13, a conserved zinc-binding protein, interacts functionally and physically with the import receptor Mia40; it improves the Erv1-dependent oxidation of Mia40 both in vivo and in vitro. PMID: 18787558
18. the cysteine residues have distinct roles and are not equally important for Mia40 function. PMID: 19011240
19. Results are consistent with the growth phenotypes of Mia40 mutant cells containing Ser replacement of the conserved cysteine residues. PMID: 19667201

Show More

Hide All

KEGG: sce:YKL195W

STRING: 4932.YKL195W