mlc Antibody

1. Mlc can be sequestered by both PtsG and NagE but that sequestration by NagE is only significant when the NagE level is high. PMID: 26293172
2. This work identifies four amino acids in the linker region which allow Mlc to distinguish between a C/G and an A/T bp at positions +/-11 of the operators. PMID: 25452338
3. Studies indicate tht control mechanism of the repressor Mlc by interaction with enzyme IIB components of the phosphoenolpyruvate: sugar phosphotransferase system. PMID: 23318733
4. Based on these findings, the authors propose a model of MtfA as a glucose-regulated peptidase activated by cytoplasmic Mlc. PMID: 22178967
5. crystal structure of Mlc, a global regulator of sugar metabolism PMID: 15929984
6. Repression by chimeric proteins Mlc confirms the importance of the C-terminal region of Mlc for both repression and inducer binding and show that the helix-turn-helix DNA-binding motif is not sufficient to interact with DNA. PMID: 18067539
7. The crystal structure of a tetrameric Mlc in a complex with four molecules of enzyme IIB(Glc) (EIIB), the cytoplasmic domain of EIICB(Glc), is reported. PMID: 18319344
8. Results show that regulation of ptsG by Mlc involves some cooperative binding of Mlc to the two Mlc operators upstream of ptsG. PMID: 18469102

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KEGG: ecj:JW1586

STRING: 316385.ECDH10B_1727