MMS19 Antibody

Datasheet

Code	CSB-PA223470XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MMS19 Polyclonal antibody

Uniprot No.

Q0WVF8

Target Names

MMS19

Alternative Names

MMS19 antibody; MET18 antibody; At5g48120 antibody; MDN11.21MMS19 nucleotide excision repair protein homolog antibody; MET18 homolog antibody; MMS19-like protein antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana MMS19 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May select specific target apoproteins to which a Fe-S cluster produced by the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) pathway is transferred.

Gene References into Functions

Study reveals that MET18 mutation caused DNA hypermethylation at more than 1000 loci, of which about 70% were overlapped with the ROS1 targeted loci, indicating a same genetic pathway. Results show that MET18 regulates active DNA demethylation by affecting the enzymatic activity of the ROS1/DME family proteins. Thus, MET18 can regulate both active DNA demethylation and DNA methylation pathways in Arabidopsis. PMID: 27193999
Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation. [MET18] PMID: 26492035

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

MET18/MMS19 family

Database Links

KEGG: ath:AT5G48120

STRING: 3702.AT5G48120.1

UniGene: At.29864

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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