MOD5 Antibody

Datasheet

Code	CSB-PA357241XA01SVG
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Target Background

Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MOD5 Polyclonal antibody

Uniprot No.

P07884

Target Names

MOD5

Alternative Names

MOD5 antibody; YOR274W antibody; tRNA dimethylallyltransferase antibody; DMATase antibody; EC 2.5.1.75 antibody; Isopentenyl-diphosphate: tRNA isopentenyltransferase antibody; IPP transferase antibody; IPPT antibody; tRNA isopentenyltransferase antibody; IPTase antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MOD5 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in the anticodon loop on a specific subset of tRNAs both in the cytosol and the mitochondrion, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). This modification optimizes the codon:anticodon fit in the ribosome and promotes translational fidelity. Competes with the farnesyl pyrophosphate synthase ERG20 for the common substrate dimethylallyl diphosphate (DMAPP).

Gene References into Functions

Mod5 protein binds to tRNA gene complexes and affects local transcriptional silencing. PMID: 23898186
identified Mod5 as a yeast prion protein and found that its prion conversion in yeast regulated the sterol biosynthetic pathway for acquired cellular resistance against antifungal agents; selective pressure by antifungal drugs on yeast facilitated the de novo appearance of Mod5 prion states for cell survival PMID: 22517861
show that Tit1p accommodates a broader range of substrates than Mod5p PMID: 21873461

Subcellular Location

Cytoplasm. Mitochondrion. Nucleus. Note=[MOD+] forms multicytoplasmic aggregates that do not colocalize to either mitochondria or nucleus.; [Isoform I]: Cytoplasm. Mitochondrion.; [Isoform II]: Cytoplasm. Nucleus.

Protein Families

IPP transferase family

Database Links

KEGG: sce:YOR274W

STRING: 4932.YOR274W

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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MOD5 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background