oma-2 Antibody

Code CSB-PA158843XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans oma-2 Polyclonal antibody
Uniprot No.
Target Names
oma-2
Alternative Names
oma-2 antibody; moe-2 antibody; ZC513.6 antibody; CCCH-type zinc finger protein oma-2 antibody; Maturation oocyte expansion protein 2 antibody; Oocyte maturation defective protein 2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans oma-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Zinc-finger RNA-binding protein that binds to 5'-UA[AU]-3' motifs in the 3'-UTR of maternal mRNAs to suppress translation in oocytes and embryos. Acts redundantly with oma-1 to control the temporal expression and distribution of maternal proteins and thereby promote meiotic progression, oocyte maturation, fertilization and embryonic development. Also, together with oma-1, is involved in P-granule distribution during embryonic development.
Gene References into Functions
  1. OMA-2 promotes expression of spn-4 and meg-1 during oocyte meiotic maturation and the oocyte-to-embryo transition. PMID: 28576864
Subcellular Location
Cytoplasm. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Tissue Specificity
Exclusively expressed in the hermaphrodite gonad. Expression only in cellulized oocytes. Widely distributed throughout gonadal oocytes from the mitotic stage to the developing diakinesis stage.
Database Links

KEGG: cel:CELE_ZC513.6

STRING: 6239.ZC513.6.1

UniGene: Cel.7680

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