Moe Antibody

1. These results indicate a critical role for Moesin in both neuronal morphogenesis and long-term memory formation. PMID: 28851405
2. The distribution of Moesin in the nucleus suggests a function in transcription and the depletion of mRNA export factors Nup98 or its interacting partner, Rae1, leads to the nuclear accumulation of Moesin, suggesting that the nuclear function of the protein is linked to mRNA export PMID: 28554770
3. Data show that Moesin upregulation influences extra-centrosome behavior and robust bipolar spindle formation. PMID: 25772448
4. Btsz and Moesin guide luminal membrane morphogenesis through organizing actin. PMID: 24413568
5. The conserved C-terminal coiled-coil domain of Slik, which is necessary and sufficient for apical localization of the kinase in epithelial cells, is not required for Moesin phosphorylation but is critical for the growth-promoting function of Slik. PMID: 26170449
6. Early endocytosis maintains normal steady-state levels of Crumbs, which recruits apical phosphorylated (active) Moesin, which in turn regulates seamless tube shape through modulation of cortical actin filaments. PMID: 25065756
7. Moesin interacts with an unusual RhoGAP, Conundrum (Conu), and recruits it to the cell cortex to negatively regulate RhoA activity. PMID: 23468526
8. Moesin stabilizes microtubules via a direct interaction at the cell cortex. PMID: 23857773
9. Wgn-Moe signaling cascade plays a key role in photoreceptor target field innervations through cell autonomous and non-cell autonomous mechanisms. PMID: 23544124
10. Drosophila melanogaster protein phosphatase type 1 beta (flapwing) co-regulates dephosphorylation and altered activity of both Merlin and Moesin. PMID: 22133918
11. This study revealed a novel mechanism for controlling salivary gland lumen size, namely through Rho1-dependent actin polymerization and distribution and downregulation of apical phosphorylated moesin. PMID: 22071107
12. the Pp1-87B phosphatase restricts high Moesin activity to early mitosis and down-regulates Moesin at the polar cortex, after anaphase onset. PMID: 21969469
13. Epithelial cell without moesin show reduced cortical actin cytoskeleton, lack of junctional markers, detach from and migrate out of the epithelium suggesting a role of moesin in the stabilization of the apical-junctional domain. (Review) PMID: 21343695
14. PtdIns(4,5)P(2) binding is essential for moesin recruitment to the membrane and for its subsequent phosphorylation. PMID: 20519583
15. Crumbs interacts with moesin and beta(Heavy)-spectrin in the apical membrane skeleton of Drosophila. PMID: 12213838
16. Dmoesin is required during oogenesis for anchoring microfilaments to the oocyte cortex. Alteration of the actin cytoskeleton resulting from Dmoesin mutations impairs the localization of maternal determinants, thus disrupting antero-posterior polarity. PMID: 12360288
17. rosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring. PMID: 12477397
18. Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity PMID: 12511959
19. reductions in Moesin levels in the wing disc cause the formation of wing-tissue vesicles and large thickenings of the vein, corresponding to breakdowns of epithelial continuity in the wing base and modifications of Hedgehog signalling in the wing blade PMID: 16682173
20. our results demonstrate a role for moesin in regulating synaptic growth in the Drosophila neuromuscular junction. PMID: 18161855
21. Changes in the activity and localization of Moesin that accompany mitotic progression contribute to the establishment of a stiff, rounded cortex at metaphase and to polar relaxation at anaphase. PMID: 18207738
22. We propose that the spatiotemporal control of moesin activation at the mitotic cortex provides localized cues to coordinate cortical contractility and microtubule interactions during cell division. PMID: 18283112
23. These findings suggest that Ribbon and Lola Like function as a novel transcriptional cassette coordinating molecular changes at the apical membrane of epithelial cells to facilitate tube elongation. PMID: 18585700
24. Results provide evidence that Dmoe RNA is a target of Lark during oogenesis and that it likely regulates either the splicing or translation of this RNA. PMID: 18958492
25. Live imaging reveals that the Drosophila actin-binding ERM protein, moesin, co-localizes with the mitotic spindle. PMID: 19592131

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KEGG: dme:Dmel_CG10701

UniGene: Dm.6642