MORC6 Antibody

Code CSB-PA164313XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MORC6 Polyclonal antibody
Uniprot No.
Target Names
MORC6
Alternative Names
MORC6 antibody; CRH6 antibody; DMS11 antibody; At1g19100 antibody; F14D16.25 antibody; Protein MICRORCHIDIA 6 antibody; AtMORC6 antibody; EC 3.6.-.- antibody; Protein CRT1-homolog 6 antibody; CRT1-h6 antibody; Protein DEFECTIVE IN MERISTEM SILENCING 11 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MORC6 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. Together with SUVH2 and SUVH9, regulates the silencing of some transposable elements (TEs). Exhibits ATPase activity. May also be involved in the regulation of chromatin architecture/condensation to maintain gene silencing. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Positive regulator of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa).
Gene References into Functions
  1. MORC6 influences RNA-directed DNA methylation and that it is not acting downstream of DNA methylation. [MORC6] PMID: 23675613
  2. Mutations in AtMORC1 and AtMORC6 cause derepression of DNA-methylated genes and transposable elements but no losses of DNA or histone methylation; AtMORC1 and AtMORC6 are members of the conserved Microrchidia (MORC) ATPase family, which are predicted to catalyze alterations in chromosome superstructure. [MORC6] PMID: 22555433
Subcellular Location
Nucleus.
Protein Families
MORC ATPase protein family
Database Links

KEGG: ath:AT1G19100

STRING: 3702.AT1G19100.1

UniGene: At.41761

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