cdc-25.2 Antibody

Code CSB-PA527363XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans cdc-25.2 Polyclonal antibody
Uniprot No.
Target Names
cdc-25.2
Alternative Names
cdc-25.2 antibody; F16B4.8 antibody; M-phase inducer phosphatase cdc-25.2 antibody; EC 3.1.3.48 antibody; Cell division cycle-related protein 25.2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans cdc-25.2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for intestinal cell division following the 16E cell stage of embryogenesis. Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1.3 and by activating the cdk-1/cyb-1 complex. Plays a role in male tail development, via regulation of the cell divisions of the ray precursor cell lineages, perhaps acting together with cell cycle regulators cyl-1, cdk-1, cyb-3, and cyd-1.
Gene References into Functions
  1. CDC-25.2 is essential for cell divisions in ray precursor cell lineages for proper male tail development PMID: 27923661
  2. timely regulation of CDC-25.2 activity is essential for the progression of specialized division cycles and development of the C. elegans intestine. PMID: 27104746
Protein Families
MPI phosphatase family
Database Links

KEGG: cel:CELE_F16B4.8

STRING: 6239.F16B4.8

UniGene: Cel.23180

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