mreC Antibody

Code CSB-PA325873XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) mreC Polyclonal antibody
Uniprot No.
Target Names
mreC
Alternative Names
mreC antibody; b3250 antibody; JW3219 antibody; Cell shape-determining protein MreC antibody; Cell shape protein MreC antibody; Rod shape-determining protein MreC antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) mreC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in formation and maintenance of cell shape. Responsible for formation of rod shape. May also contribute to regulation of formation of penicillin-binding proteins.
Gene References into Functions
  1. We found that cells depleted of mreBCD became spherical, enlarged and finally lysed. Depletion of each mre gene separately conferred similar gross changes in cell morphology and viability. PMID: 15612918
  2. three promoters contributed to the expression of mreBCD PMID: 17090951
  3. Cells lacking mreC were fully viable and propagated as small spheres under conditions of slow mass increase but formed large nondividing spheroids with noncanonical FtsZ assembly patterns at higher mass doubling rates. PMID: 17993535
Subcellular Location
Cell inner membrane; Single-pass membrane protein.
Protein Families
MreC family
Database Links

KEGG: ecj:JW3219

STRING: 316407.85676042

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