MRJP3 Antibody

Code CSB-PA615027XA01DNK
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Product Details

Full Product Name
Rabbit anti-Apis mellifera (Honeybee) MRJP3 Polyclonal antibody
Uniprot No.
Target Names
MRJP3
Alternative Names
MRJP3 antibody; Major royal jelly protein 3 antibody; MRJP-3 antibody; Bee-milk protein antibody; Royal jelly protein RJP57-1 antibody
Raised in
Rabbit
Species Reactivity
Apis mellifera (Honeybee)
Immunogen
Recombinant Apis mellifera (Honeybee) MRJP3 protein
Immunogen Species
Apis mellifera (Honeybee)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Secreted RNA-binding protein required to concentrate, stabilize and enhance environmental RNA bioavailability in the honeybee royal jelly. Acts as a RNA-aggregating protein: binds 18 nucleotides and longer single- and double-stranded RNA (ssRNA and dsRNA, respectively) in a non-specific manner. RNA-binding drives super-order assembly of oligomers into extracellular ribonucleoprotein granules that concentrate, protect and enhance RNA uptake granules, facilitating RNA transfer among bees.
Gene References into Functions
  1. Among 675 different proteins after MRJP1 expression, 646 were down-regulated and significantly enriched in pathways implicated in VSMC contraction and migration, which suggest MRJP1 lowers VSMC contraction and migration by inhibiting muscle filament movement. This is the first report integrating MRJP1 into VSMC, revealing the function and mechanism correlated with anti-hypertensive activity. PMID: 27444336
Subcellular Location
Secreted.
Protein Families
Major royal jelly protein family
Tissue Specificity
Hypopharyngeal glands of nurse honey bees.
Database Links

KEGG: ame:406121

UniGene: Ame.731

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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