msh-5 Antibody

Code CSB-PA613896XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans msh-5 Polyclonal antibody
Uniprot No.
Target Names
msh-5
Alternative Names
msh-5 antibody; F09E8.3 antibody; MutS protein homolog 5 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans msh-5 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. Together with him-14 and zhp-3 plays a role in the activation of DNA damage-dependent apoptosis at the DNA damage checkpoint in pachytene cells.
Gene References into Functions
  1. Results report a specific role for IFE-2 in a conserved temperature-sensitive meiotic process that results in an increase in MSH-5 protein levels. PMID: 20530576
Subcellular Location
Chromosome.
Protein Families
DNA mismatch repair MutS family
Tissue Specificity
Expressed in the germline.
Database Links

KEGG: cel:CELE_F09E8.3

STRING: 6239.F09E8.3

UniGene: Cel.19456

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