MSL10 Antibody

Code CSB-PA864891XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MSL10 Polyclonal antibody
Uniprot No.
Target Names
MSL10
Alternative Names
MSL10; At5g12080; F14F18.230; MXC9.3; Mechanosensitive ion channel protein 10; Mechanosensitive channel of small conductance-like 10; MscS-Like protein 10; AtMSL10
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MSL10 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.
Gene References into Functions
  1. results suggest that MSL10 is involved in the wound-triggered early signal transduction pathway and possibly in regulating the positive feedback synthesis of JA. PMID: 26356550
  2. The plant-specific N-terminal domain of MSL10 is capable of inducing cell death, this activity is regulated by phosphorylation, and MSL10 has two separable activities-one as an ion channel and one as an inducer of cell death. PMID: 25052715
  3. MSL10 demonstrated asymmetric activation/inactivation kinetics, with the channel closing at substantially lower tensions than channel opening. PMID: 23112188
  4. MSL9 and MSL10 are required for mechanosensitive channel activities detected in protoplasts derived from root cells. [MSL10] PMID: 18485707
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
MscS (TC 1.A.23) family
Tissue Specificity
Detected in the root tip and throughout the vasculature of the root and leaf.
Database Links

KEGG: ath:AT5G12080

STRING: 3702.AT5G12080.1

UniGene: At.28024

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