MsrA Antibody

Code CSB-PA362502XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) MsrA Polyclonal antibody
Uniprot No.
Target Names
MsrA
Alternative Names
Eip71CD antibody; Eip28/29 antibody; MsrA antibody; CG7266 antibody; Peptide methionine sulfoxide reductase antibody; EC 1.8.4.11 antibody; Ecdysone-induced protein 28/29 kDa antibody; Methionine-S-sulfoxide reductase antibody; Peptide-methionine antibody; S)-S-oxide reductase antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) MsrA protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reduction of methionine sulfoxide in proteins to methionine. Does not catalyze the reverse reaction involving the oxidation of methionine residues.
Gene References into Functions
  1. overexpression of dmsrA in fat body cells caused FOXO to translocate to the nucleus, implying that this possible positive feedback loop between dmsrA and FOXO could potentiate the antioxidant activity of dmsrA and increase the lifespan PMID: 20655917
  2. Reaction mechanism, evolutionary analysis, and role of zinc for methionine sulfoxide reductase PMID: 12145281
  3. Hormonal regulation of MsrA is implicated in conferring protection against oxidative stress in the Drosophila model. PMID: 17239346
  4. MsrA and MsrB, the two proteins with similar function in antioxidant protein repair, have different effects on aging in fruit flies. PMID: 19409408
Protein Families
MsrA Met sulfoxide reductase family
Database Links

KEGG: dme:Dmel_CG7266

STRING: 7227.FBpp0303210

UniGene: Dm.2545

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