Name: msrP Antibody
Brand: CUSABIO
SKU: CSB-PA301197XA01ENV

Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) msrP Polyclonal antibody

Uniprot No.

P76342

Target Names

msrP

Alternative Names

msrP antibody; yedY antibody; b1971 antibody; JW1954 antibody; Protein-methionine-sulfoxide reductase catalytic subunit MsrP antibody; EC 1.8.5.- antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

A synthesized peptide derived from Escherichia coli (strain K12) msrP protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, Dot blot (guaranteed specific to the immunizing peptide)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

①. 100ug * KLH-conjugated peptide paired with 100ug * BSA-conjugated peptide (positive control);
②. 1ml*pre-immune serum (used as negative control) for free;
③. Rabbit polyclonal antibodies purified by Antigen Affinity;

Quality Guarantee

1. CUSABIO guarantees the antibody purity > 95% confirmed by SDS-PAGE.
2. CUSABIO guarantees the antibody titer > 1: 64,000 confirmed by ELISA.
3. CUSABIO guarantees to offer Peptide-specific Dot blot.
4. CUSABIO guarantees 100% risk-free: No qualified antibody, no charge.

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide. Can catalyze the reduction of a variety of substrates in vitro, including dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase.

Gene References into Functions

The study reports on the structural characterization using X-ray absorption spectroscopy of the molybdenum site of Escherichia coli YedY. PMID: 21190336
Study investigated the atomic structure of the molybdenum site in YedY by X-ray absorption spectroscopy PMID: 21190337
YedY and its many orthologues may represent a new type of membrane-associated bacterial reductase. PMID: 15355966
YedY is a sulfite oxidase catalytic subunit with a twin arginine leader sequence for export to the periplasm by the Tat translocation system. PMID: 16042411

Subcellular Location

Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.

Protein Families

MsrP family

Database Links

KEGG: ecj:JW1954

STRING: 316407.85675174

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

Code	CSB-PA301197XA01ENV
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

msrP Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background