mtnN Antibody

Code CSB-PA482703XA01EOP
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O81 (strain ED1a) mtnN Polyclonal antibody
Uniprot No.
Target Names
mtnN
Alternative Names
mtnN antibody; ECED1_0166 antibody; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase antibody; MTA/SAH nucleosidase antibody; MTAN antibody; EC 3.2.2.9 antibody; 5'-deoxyadenosine nucleosidase antibody; DOA nucleosidase antibody; dAdo nucleosidase antibody; EC 3.2.2.- antibody; 5'-methylthioadenosine nucleosidase antibody; MTA nucleosidase antibody; S-adenosylhomocysteine nucleosidase antibody; AdoHcy nucleosidase antibody; SAH nucleosidase antibody; SRH nucleosidase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O81 (strain ED1a)
Immunogen
Recombinant Escherichia coli O81 (strain ED1a) mtnN protein
Immunogen Species
Escherichia coli O81 (strain ED1a)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
Protein Families
PNP/UDP phosphorylase family, MtnN subfamily
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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