mtnN Antibody

Code CSB-PA946582XA01FQR
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) mtnN Polyclonal antibody
Uniprot No.
Target Names
mtnN
Alternative Names
mtnN antibody; c0195 antibody; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase antibody; MTA/SAH nucleosidase antibody; MTAN antibody; EC 3.2.2.9 antibody; 5'-deoxyadenosine nucleosidase antibody; DOA nucleosidase antibody; dAdo nucleosidase antibody; EC 3.2.2.- antibody; 5'-methylthioadenosine nucleosidase antibody; MTA nucleosidase antibody; S-adenosylhomocysteine nucleosidase antibody; AdoHcy nucleosidase antibody; SAH nucleosidase antibody; SRH nucleosidase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Immunogen
Recombinant Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) mtnN protein
Immunogen Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
Protein Families
PNP/UDP phosphorylase family, MtnN subfamily
Database Links

KEGG: ecc:c0195

STRING: 199310.c0195

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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