MUCL1 Antibody

Code CSB-PA842658XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MUCL1 Polyclonal antibody
Uniprot No.
Target Names
MUCL1
Alternative Names
mucin like 1 antibody; mucin-like 1 antibody; Mucin-like protein 1 antibody; MUCL1 antibody; MUCL1_HUMAN antibody; Protein BS106 antibody; Small breast epithelial mucin antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) MUCL1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May play a role as marker for the diagnosis of metastatic breast cancer.
Gene References into Functions
  1. an important role for MUCL1 in the proliferation of breast cancer cells PMID: 26725324
  2. SBEM has the potential to be a specific marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer. PMID: 20364301
  3. identification as possible new breast tumor biomarker PMID: 15684711
  4. octamer-binding transcription factors participate in the strong expression of SBEM gene in breast tissues PMID: 16720387
  5. SBEM may identify a unique subset of breast cancers with poor prognosis and have implications for therapeutic management. PMID: 18269587
  6. results demonstrate that SBEM mRNA may be an important marker for targeting breast cancer micrometastasis PMID: 18497056
  7. The SBEM might a suitable marker for molecular detection of ITCs in BM in breast cancer patients. Analysis of prognostic value for SBEM mRNA-based assay should take into account the heterogeneity and different molecular subtypes of breast cancer. PMID: 19221791

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Subcellular Location
Secreted. Membrane.
Tissue Specificity
Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic
Database Links

HGNC: 30588

OMIM: 610857

KEGG: hsa:118430

STRING: 9606.ENSP00000311364

UniGene: Hs.348419

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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