mukF Antibody

1. activity of MukB requires DNA binding by the head domains of the protein but does not require either ATP or its partner proteins MukE or MukF. The ability of MukB to mediate DNA catenation underscores its potential for bringing distal regions of a chromosome together. PMID: 27697840
2. MatP regulates the action of topoisomerase IV and MukBEF in chromosome segregation. PMID: 26818444
3. Taken together, the data implicate MukBEF as a key component of the DNA segregation process by acting in concert with TopoIV to promote decatenation and positioning of newly replicated oris. PMID: 24520061
4. MukBEF complexes may undergo multiple cycles of ATP hydrolysis without being released from DNA, analogous to the behavior of well-characterized molecular motors. PMID: 23112333
5. findings show here that MukBEF generates and maintains the cellular positioning of chromosome loci independently of DNA replication. PMID: 22753058
6. Competing MukB-MukE and MukE-MukE interactions may regulate the formation of higher-order structures of bacterial condensin. PMID: 21855551
7. The crystal structure of the N-terminal 287 amino acids of MukF at 2.9 A resolution shows that this region folds into a winged-helix domain and an extended coiled-coil domain that self-associate to form a stable, doubly domain-swapped dimer. PMID: 15902272
8. MukEF Is required for stable association of MukB with the chromosome. PMID: 17644586

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KEGG: ecj:JW0905

STRING: 316385.ECDH10B_0992