Mvl Antibody

Code CSB-PA344188XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Mvl Polyclonal antibody
Uniprot No.
Target Names
Mvl
Alternative Names
Mvl antibody; CG3671 antibody; Protein Malvolio antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Mvl protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Putative transporter required for normal taste behavior. May be a nitrite/nitrate transporter.
Gene References into Functions
  1. Mvl transporter affects food choice behavior via the regulation of dopaminergic innervation of the mushroom bodies. PMID: 28220999
  2. Flies mutant for dNRAMP were protected from virus infection. dNRAMP2 facilitates infection and binding of Sindbis virus in mammalian cells. PMID: 21843867
  3. MCO3 mutants had a mild accumulation of copper, which was suppressed in Mvl mutants, revealing a reciprocal genetic interaction between the two genes. PMID: 21346125
  4. The expression of Mvl in the gut and Malpighian tubules within D. melanogaster is reported; the conservation of function between Nramp2 and Mvl in flies and mammals is also discussed. PMID: 16651563
  5. Mvl is a functional Cu transporter necessary for optimal viability at the cellular and organismal levels. PMID: 18281333

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
NRAMP family
Tissue Specificity
Expressed in macrophages and in the nervous system.
Database Links

KEGG: dme:Dmel_CG3671

STRING: 7227.FBpp0303079

UniGene: Dm.2388

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