NAB3 Antibody

1. Kinetic cross-linking and analysis of cDNAs uncovers a role for Nab3 in determining gene expression profiles during stress. PMID: 28400552
2. Study analyzed the functional role of the prion-like low complexity domains (LCDs) of Nab3, which can assemble into a robust amyloid form. Results show that Nab3 LCD can be exchanged for the low complexity regions of other proteins as the prion protein Sup35, or the RNA-binding protein, Hrp1. Also, its C-terminus seems more complex than previously appreciated. PMID: 29023495
3. a role for Nab3 in regulating the cellular response to nutrient availability PMID: 22431520
4. Nab3 protein contains a self-assembly domain found in human heterogeneous nuclear ribonucleoprotein-C (hnRNP-C) that is necessary for transcription termination PMID: 23192344
5. Structural homology modeling suggests that the carboxy-terminal amino acids of Nab3 forms an alpha-helical multimerization domain that helps assemble it onto an RNA substrate. PMID: 22564898
6. the solution structure of the RNA-recognition motif (RRM) of Nab3 in complex with a UCUU oligonucleotide, representing the Nab3 termination element PMID: 21084293
7. The crystal structure of the Nab3 RNA recognition motif reveals clear density for a UCU trinucleotide and a fourth putative U binding site. PMID: 20805243

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KEGG: sce:YPL190C

STRING: 4932.YPL190C