NAC017 Antibody

Code CSB-PA230662XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) NAC017 Polyclonal antibody
Uniprot No.
Target Names
NAC017
Alternative Names
NAC017 antibody; NTL7 antibody; RAO2 antibody; At1g34190 antibody; F23M19.13 antibody; NAC domain-containing protein 17 antibody; ANAC017 antibody; Protein NTM1-like 7 antibody; Protein REGULATORS OF AOX1A 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana NAC017 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction. Binds directly to AOX1A promoter. Mediates mitochondrial retrograde signaling.
Gene References into Functions
  1. The AtNTL7 fragment is cleaved from the ER membrane under ER stress and translocates into the nucleus to induce downstream ER-stress responsive genes. [AtNTL7] PMID: 28088515
  2. The role of ANAC017/PAP-dependent retrograde signalling pathways are reviewed. PMID: 28498364
  3. ANAC017 is a key regulator of responses to chemical mitochondrial inhibition. PMID: 27208304
  4. Retrograde signalling caused by heritable mitochondrial dysfunction is partially mediated by ANAC017 and improves plant performance. PMID: 27425258
  5. ANAC017 plays a major role in responses to hydrogen peroxide-mediated oxidative stress. PMID: 24045018

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Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
Tissue Specificity
Expressed in roots, rosette leaves, cauline leaves, shoot apex, stems and flowers.
Database Links

KEGG: ath:AT1G34190

STRING: 3702.AT1G34190.1

UniGene: At.11394

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