NAH Antibody

Code CSB-PA327561XA01SXV
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Product Details

Full Product Name Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) sod2 Polyclonal antibody
Uniprot No. P36606
Target Names sod2
Alternative Names sod2 antibody; SPAC977.10 antibody; Na(+)/H(+) antiporter antibody
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NAH protein
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
Sodium export from cell, takes up external protons in exchange for internal sodium ions. Involved in regulation of pH.
Gene References into Functions
  1. Structure and function of an Na(+)/H(+) antiporter has been described. (Review) PMID: 29219228
  2. results demonstrate that cysteines in the Sod2 protein can be changed to serine residues resulting in an expressed, functional protein PMID: 24104454
  3. TM IV of Sod2 is critical to transport and may be involved in cation binding or conformational changes of the protein. PMID: 23836910
  4. Role of nine polar, membrane associated amino acids in the ability of the protein to confer salt tolerance. The mutation P146A did not convey salt tolerance nearly as effectively as the wild type and did not extrude Na(+) as well as the wild type. PMID: 19171118
Subcellular Location Membrane; Multi-pass membrane protein.
Protein Families Fungal Na(+)/H(+) exchanger family
Database Links

KEGG: spo:SPAC977.10

STRING: 4896.SPAC977.10.1

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