Name: NAH Antibody
Brand: CUSABIO
SKU: CSB-PA327561XA01SXV

Product Details

Full Product Name	Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) sod2 Polyclonal antibody
Uniprot No.	P36606
Target Names	sod2
Alternative Names	sod2 antibody; SPAC977.10 antibody; Na(+)/H(+) antiporter antibody
Raised in	Rabbit
Species Reactivity	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen	Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NAH protein
Immunogen Species	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (14-16 weeks)

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Target Background

Function (From Uniprot)	Sodium export from cell, takes up external protons in exchange for internal sodium ions. Involved in regulation of pH.
Gene References into Functions	Structure and function of an Na(+)/H(+) antiporter has been described. (Review) PMID: 29219228 results demonstrate that cysteines in the Sod2 protein can be changed to serine residues resulting in an expressed, functional protein PMID: 24104454 TM IV of Sod2 is critical to transport and may be involved in cation binding or conformational changes of the protein. PMID: 23836910 Role of nine polar, membrane associated amino acids in the ability of the protein to confer salt tolerance. The mutation P146A did not convey salt tolerance nearly as effectively as the wild type and did not extrude Na(+) as well as the wild type. PMID: 19171118
Subcellular Location	Membrane; Multi-pass membrane protein.
Protein Families	Fungal Na(+)/H(+) exchanger family
Database Links	KEGG: spo:SPAC977.10 STRING: 4896.SPAC977.10.1

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Code	CSB-PA327561XA01SXV
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NAH Antibody