NAP1 Antibody

1. Study found that Nap1 efficiently promotes disassembly of adjacent nucleosomes with which RSC collides and not the disassembly of nucleosomes mobilized by RSC. These results suggests a mechanism by which Nap1 is recruited to actively transcribed regions and assists in the passage of the transcription complex through chromatin, and it provides a novel mechanism for the coordinated action of RSC and Nap1. PMID: 27273866
2. these results define the distinct roles for histone chaperones Chz1 and Nap1 to regulate Htz1 incorporation into chromatin. PMID: 25338502
3. Nap1 and DNA directly compete for H2A-H2B histones. Nap1 stabilizes the fold of H2A-H2B histones PMID: 23973327
4. findings show that Nap1 and Vps75 regulate cryptic transcription observed in the absence of Ctk1. Rtt109 acetylation of H3 K9 also plays a role in this pathway, and both Vps75 and Nap1 promote acetylation of H3 in the ORF. PMID: 23401858
5. present evidence for a paradigm in which nucleosome assembly requires the elimination of competing, nonnucleosomal histone-DNA interactions by Nap1. PMID: 20347425
6. the histone chaperones Nap1 and Chz1 have separate Htz1-dependent and -independent functions PMID: 19929865
7. structural analysis of nucleosome assembly protein 1 PMID: 16432217
8. A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of NAP1. PMID: 18068721
9. These data show that Nap1 phosphorylation by CK2 appears to regulate Nap1 localization and is required for normal progression through S phase. PMID: 18086883
10. Nap1 regulates transcription of PHO5 & interacts directly with Yra1 & genetically with other TREX complex components & Mex67. Nap1 connects transcription elongation, chromatin assembly, & messenger RNP complex biogenesis. PMID: 18227150
11. analysis of a thermodynamic model for Nap1-histone interactions PMID: 18728017

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KEGG: sce:YKR048C

STRING: 4932.YKR048C