NAV3 Antibody

1. Together, our findings suggest an important role for miR-21 in the progression of HCC, which negatively regulated Navigator-3 in the migration of HCC. PMID: 26210448
2. The authers propose that NAV3 inhibits breast cancer progression by regulating microtubule dynamics, biasing directionally persistent rather than random migration, and inhibiting locomotion of initiated cells. PMID: 25678558
3. Data indicate that neuron navigator 3 (NAV3) may be a potential new prognostic biomarker and a potential therapeutic target. PMID: 23097141
4. NAV3 has a role in linking tissue inflammation to cancer development in the colon. PMID: 22173670
5. characterized copy number changes of NAV3 in 24 basal cell cancers, eight squamous cell cancers and eight non-malignant inflammatory skin lesions PMID: 21995814
6. NAV3 gene would not be frequently deleted in cutaneous type leukemia/lymphoma including those with mycosis fungoides-like manifestations PMID: 19626031
7. Allelic NAV3 aberrations (LOH or deletion by FISH were identified in 44% of the subcutaneous panniculitis-like T-cell lymphoma samples. PMID: 18337827
8. An imbalanced fluorescence in situ hybridization pattern between NAV3 and pericentromeric control probes was seen in three patients in accordance with CGH array data. No NAV3 specific breakpoint or partial deletion was detected. PMID: 18509363

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HGNC: 15998

OMIM: 611629

KEGG: hsa:89795

STRING: 9606.ENSP00000446132

UniGene: Hs.655301