sel-2 Antibody

Datasheet

Code	CSB-PA621176XA01CXY
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Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans sel-2 Polyclonal antibody

Uniprot No.

Q19317

Target Names

sel-2

Alternative Names

sel-2 antibody; F10F2.1 antibody; Putative neurobeachin homolog antibody; Suppressor enhancer of lin-12 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans sel-2 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells.

Gene References into Functions

sel-2 is involved in endosomal traffic and may be involved in efficient delivery of cell surface proteins to the lysosome. PMID: 17215302

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Nucleus.

Protein Families

WD repeat neurobeachin family

Tissue Specificity

Expressed in vulval precursor cells and rectal epithelia in L2 and L3 larvae. In L4 larvae, expression is seen in intestinal epithelial cells.

Database Links

KEGG: cel:CELE_F10F2.1

STRING: 6239.F10F2.1

UniGene: Cel.10609

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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sel-2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background