STO1 Antibody

Code CSB-PA327292XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) STO1 Polyclonal antibody
Uniprot No.
Target Names
STO1
Alternative Names
STO1 antibody; CBC1 antibody; CBP80 antibody; GCR3 antibody; SUT1 antibody; YMR125W antibody; YM8564.07 antibody; YM9553.01 antibody; Nuclear cap-binding protein complex subunit 1 antibody; 80 kDa nuclear cap-binding protein antibody; CBP80 antibody; NCBP 80 kDa subunit antibody; Glycolysis regulation protein 3 antibody; Protein SUT1 antibody; Suppressor of TOP1 protein antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) STO1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the CBC complex, which binds co-transcriptionally to the 5'-cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs. The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation. Together with NPL3, the CBC complex is required for export of mRNAs out of the nucleus. The CBC complex is also involved in nuclear mRNA degradation, probably by directing the mRNAs to the sites of degradation. Affects replication of the positive-strand RNA virus BMV.
Gene References into Functions
  1. our results indicate that binding of Cbc1 to the capped mRNAs is necessary for the accumulation of specific activators as well as PIC components at the promoters of genes whose expression requires high and rapid transcription. PMID: 26775127
  2. Cbc1-mediated translation is necessary for the rapid translation of osmostress-protective proteins under osmotic stress PMID: 22072789
  3. Cbp80 plays distinct roles in the recognition of the intron by U1 and U2 snRNP. PMID: 20801768
Subcellular Location
Nucleus. Cytoplasm, perinuclear region.
Protein Families
NCBP1 family
Database Links

KEGG: sce:YMR125W

STRING: 4932.YMR125W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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